Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantoic Acid SCHEMBL7781736 | 0.79 | PTGS1 (0.48) | PTGS1KCNH2VNN1ALDH1A1 | |
| SCHEMBL18611857 | 0.79 | ALDH1A1 (0.32) | PTGS1KCNH2ALDH1A1TDP1 | |
| Pantoic Acid SCHEMBL29112230 | 0.79 | PTGS1 (0.48) | PTGS1KCNH2VNN1ALDH1A1 | |
| SCHEMBL1781697 | 0.79 | ALDH1A1 (0.32) | PTGS1KCNH2ALDH1A1TDP1 | |
| Pantoic Acid SCHEMBL213981 | 0.79 | PTGS1 (0.48) | PTGS1KCNH2VNN1ALDH1A1 | |
| Pantoic Acid SCHEMBL213982 | 0.79 | PTGS1 (0.48) | PTGS1KCNH2VNN1ALDH1A1 | |
| Pantoic Acid SCHEMBL11575367 | 0.77 | PTGS1 (0.47) | PTGS1KCNH2VNN1ALDH1A1 | |
| Pantoic Acid SCHEMBL11576289 | 0.77 | PTGS1 (0.47) | PTGS1KCNH2VNN1ALDH1A1TDP1 | |
| Pantoic Acid SCHEMBL9630838 | 0.77 | PTGS1 (0.47) | PTGS1KCNH2VNN1ALDH1A1 | |
| Pantoic Acid SCHEMBL11575357 | 0.77 | PTGS1 (0.47) | PTGS1KCNH2VNN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |