Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077515 | 1.00 | CACNA1B (0.36) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10074290 | 0.93 | CTSS (0.40) | PTPN1SCN9ACTSSCTSKPPARA | |
| SCHEMBL10074282 | 0.93 | CTSS (0.40) | PTPN1SCN9ACTSSCTSKPPARA | |
| SCHEMBL10077061 | 0.92 | CACNA1B (0.36) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10077510 | 0.92 | CACNA1B (0.36) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10074143 | 0.92 | CACNA1B (0.36) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10074278 | 0.91 | CACNA1B (0.35) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10074470 | 0.91 | SYK (0.40) | PTPN1SCN9ACTSSCTSKPPARA | |
| SCHEMBL10074276 | 0.90 | CACNA1B (0.35) | CACNA1BPTPN1SCN9ACTSSCTSK | |
| SCHEMBL10077512 | 0.90 | CACNA1B (0.35) | CACNA1BPTPN1SCN9ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |