⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49584 | 1.00 | — | — | |
| SCHEMBL24404787 | 1.00 | — | — | |
| SCHEMBL10587012 | 0.86 | KDM4E (0.31) | — | |
| Acetic Acid SCHEMBL17385972 | 0.86 | KDM4E (0.42) | — | |
| SCHEMBL8367174 | 0.84 | KDM4E (0.30) | — | |
| SCHEMBL18429072 | 0.84 | KDM4E (0.30) | — | |
| SCHEMBL6859763 | 0.82 | KDM4E (0.47) | — | |
| SCHEMBL5073009 | 0.81 | KDM4E (0.39) | — | |
| Propionic Acid SCHEMBL5079079 | 0.81 | KDM4E (0.39) | — | |
| Methacrylic Acid SCHEMBL1947733 | 0.79 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372498-A1 | PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND | UPPTHERA (KR) | 2023-11-23 | — | — | US | disclosed |
| EP-2100142-B1 | COMPOSITION, DEVICE AND ASSOCIATED METHOD | GEN ELECTRIC (US) | 2012-02-08 | — | — | EP | disclosed |