SCHEMBL10076064

SCHEMBL10076064

CCC(=O)N[C@H](C)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CYP2C9 P11712 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
RECQL P46063 3/20 0.39
XBP1 P17861 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.37
CA14 Q9ULX7 1/20 0.37
NPSR1 Q6W5P4 5/20 0.36
ALDH1A1 P00352 3/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 4/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2D6 P10635 1/20 0.36
CTSK P43235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4815596 0.85 CA1 (0.40) CA1CA2CA7HRH3RECQL
SCHEMBL4805063 0.85 CA1 (0.40) CA1CA2CA7HRH3RECQL
SCHEMBL4805058 0.85 CA1 (0.40) CA1CA2CA7HRH3RECQL
SCHEMBL4815585 0.85 CA1 (0.40) CA1CA2CA7HRH3RECQL
SCHEMBL19245755 0.83 CA1 (0.39) CA1CA2CA7HRH3RECQL
SCHEMBL31461515 0.83 CA1 (0.39) CA1CA2CA7HRH3RECQL
SCHEMBL15223622 0.83 CA1 (0.39) CA1CA2CA7RECQLXBP1
SCHEMBL18913932 0.83 CA1 (0.39) CA1CA2CA7HRH3RECQL
SCHEMBL14498328 0.82 GAA (0.45) CYP2C9HRH3NPSR1POLBMAPT
SCHEMBL31421853 0.82 FAAH (0.47) HRH3ALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312564-A1 AROMATIC RING-LACTAM COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI RINGENE BIOPHARMA CO., LTD. (CN) 2023-10-05 US disclosed
US-8093231-B2 Sulfonylethyl phosphorodiamidates TELIK, INC. (US) 2012-01-10 US disclosed
US-20080039429-A1 SULFONYLETHYL PHOSPHORODIAMIDATES TELIK, INC. 2008-02-14 US disclosed
US-7262182-B2 Sulfonylethyl phosphorodiamidates TELIK, INC. (US) 2007-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312564-A1 AROMATIC RING-LACTAM COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF WEE1, WEE2, WASF2 CA1 4660/4885CA2 4651/4885CA7 4253/4885
US-20080039429-A1 SULFONYLETHYL PHOSPHORODIAMIDATES MTAP, TYMP, PHOSPHO1 CA1 4434/4885CA2 3159/4885CA7 2660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.