Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572344 | 0.84 | CDC7 (0.33) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| SCHEMBL29544632 | 0.76 | CDC7 (0.36) | CDC7 | |
| SCHEMBL20662112 | 0.76 | CDC7 (0.36) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| Hydrochloric Acid SCHEMBL18209645 | 0.74 | ALOX5 (0.35) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| SCHEMBL18632622 | 0.73 | CDC7 (0.34) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| SCHEMBL9938070 | 0.72 | CDC7 (0.33) | CDC7ALOX5ALOX5APFEN1 | |
| SCHEMBL18655523 | 0.72 | CDC7 (0.33) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| SCHEMBL1007694 | 0.72 | ADORA2A (0.31) | — | |
| SCHEMBL18655531 | 0.72 | ALOX5 (0.34) | CDC7ALOX5ALOX5APFEN1PARP1 | |
| SCHEMBL6386717 | 0.70 | GAA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | CDC7 3270/4885ALOX5 3983/4885ALOX5AP 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.