Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL313669 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL67458 | 0.96 | — | — | |
| Trimethylammonium SCHEMBL28154322 | 0.92 | ALDH1A1 (0.39) | — | |
| SCHEMBL14112035 | 0.91 | — | — | |
| SCHEMBL5944 | 0.91 | — | — | |
| SCHEMBL9389522 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL7070777 | 0.87 | — | — | |
| SCHEMBL21407669 | 0.87 | — | — | |
| Lithium SCHEMBL1395029 | 0.87 | — | — | |
| Water SCHEMBL11297203 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065541-A1 | MICROEMULSIONS AND METHODS OF USE | MOROCCANOIL ISRAEL, LTD. (IL) | 2020-04-02 | — | — | WO | claimed |
| CN-104884198-B | The method for preparing the hollow metal nanometer particle being supported on carrier | LG化学株式会社 | 2017-11-17 | — | — | CN | claimed |
| US-20120003319-A9 | COMPOSITIONS FOR SITE-SPECIFIC DELIVERY OF IMATINIB AND METHODS OF USE | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2012-01-05 | — | — | US | claimed |
| EP-2271316-A2 | FENOFIBRATE DOSAGE FORMS | Elan Pharma International Limited (IE) | 2011-01-12 | — | — | EP | claimed |
| EP-2268265-A2 | COMPOSITIONS FOR SITE-SPECIFIC DELIVERY OF IMATINIB AND METHODS OF USE | Elan Pharma International Limited (IE) | 2011-01-05 | — | — | EP | claimed |
| US-7842232-B2 | Sterilization of dispersions of nanoparticulate active agents with gamma radiation | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2010-11-30 | — | — | US | claimed |
| US-20090269400-A1 | Nanoparticulate and Controlled Release Compositions Comprising a Cephalosporin | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2009-10-29 | — | — | US | claimed |
| WO-2009120919-A2 | FENOFIBRATE DOSAGE FORMS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2009-10-01 | — | — | WO | claimed |
| WO-2009117401-A2 | COMPOSITIONS FOR SITE-SPECIFIC DELIVERY OF IMATINIB AND METHODS OF USE | ELAN PHARAMA INTERNATIONAL LIMITED (IE) | 2009-09-24 | — | — | WO | claimed |
| US-20090238884-A1 | COMPOSITIONS FOR SITE-SPECIFIC DELIVERY OF IMATINIB AND METHODS OF USE | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2009-09-24 | — | — | US | claimed |
| EP-1855651-A1 | NANOPARTICULATE COMPOSITIONS OF HETEROCYCLIC AMIDE DERIVATIVES | Elan Pharma International Limited (IE) | 2007-11-21 | — | — | EP | claimed |
| WO-2007100466-A2 | NANOPARTICULATE CARVEDILOL FORMULATIONS | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2007-09-07 | — | — | WO | claimed |
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| US-20060210638-A1 | Injectable compositions of nanoparticulate immunosuppressive compounds | ELAN PHARMA INTERNATIONAL LIMITED | 2006-09-21 | — | — | US | claimed |
| WO-2006096462-A1 | NANOPARTICULATE COMPOSITIONS OF HETEROCYCLIC AMIDE DERIVATIVES | ELAN PHARMA INTERNATIONAL LIMITED (IE) | 2006-09-14 | — | — | WO | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |
| US-20050233001-A1 | Nanoparticulate megestrol formulations | ELAN PHARMA INTERNATIONAL LTD. | 2005-10-20 | — | — | US | claimed |
| US-20050004049-A1 | Novel griseofulvin compositions | ELAN PHARMA INTERNATIONAL LIMITED | 2005-01-06 | — | — | US | claimed |
| US-20040033202-A1 | Nanoparticulate sterol formulations and novel sterol combinations | ELAN PHARMA INTERNATIONAL, LTD. | 2004-02-19 | — | — | US | claimed |
| US-20030224058-A1 | Fibrate particles of an effective average particle size of less than 2000 nm. having a stabilizer associated with the surface; improved pharmacokinetic profiles and reduced fed/fasted variability. | ELAN PHARMA INTERNATIONAL, LTD. | 2003-12-04 | — | — | US | claimed |