Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430142 | 0.89 | CDK2 (0.36) | CDK2CCNE2CCNE1CSNK1DCKS1B | |
| SCHEMBL13074313 | 0.84 | CCNE2 (0.36) | CDK2CCNE2CCNE1CKS1BSKP1 | |
| SCHEMBL10077167 | 0.82 | CCNE2 (0.39) | CDK2CCNE2CCNE1HDAC1BRD4 | |
| SCHEMBL13074135 | 0.82 | CKS1B (0.34) | CDK2CCNE2CCNE1CSNK1DCKS1B | |
| SCHEMBL23892831 | 0.82 | HPRT1 (0.43) | — | |
| SCHEMBL10077170 | 0.80 | CCNE2 (0.35) | CDK2CCNE2CCNE1CKS1BSKP1 | |
| SCHEMBL10077166 | 0.80 | ADORA2A (0.36) | CSNK1DCKS1BSKP1SKP2DOT1L | |
| SCHEMBL10077177 | 0.78 | CCNE1 (0.40) | CDK2CCNE2CCNE1CSNK1DCKS1B | |
| SCHEMBL430210 | 0.78 | CCNE2 (0.38) | CDK2CCNE2CCNE1CKS1BSKP1 | |
| SCHEMBL13074311 | 0.76 | TLR7 (0.37) | CDK2CCNE2CCNE1CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011114-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2012-01-26 | — | — | WO | disclosed |