Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13037052 | 0.90 | TLR7 (0.36) | ADORA2AADORA1ADORA3DOT1LCKS1B | |
| SCHEMBL10076893 | 0.80 | CDK2 (0.34) | DOT1LCKS1BSKP1SKP2CSNK1D | |
| SCHEMBL13074135 | 0.80 | CKS1B (0.34) | ADORA2AADORA1ADORA3DOT1LCKS1B | |
| SCHEMBL23892831 | 0.80 | HPRT1 (0.43) | — | |
| SCHEMBL10077170 | 0.78 | CCNE2 (0.35) | DOT1LCKS1BSKP1SKP2TLR7 | |
| SCHEMBL13074313 | 0.78 | CCNE2 (0.36) | DOT1LCKS1BSKP1SKP2TLR7 | |
| SCHEMBL10077165 | 0.77 | HDAC1 (0.36) | CKS1BSKP1SKP2 | |
| SCHEMBL10077177 | 0.76 | CCNE1 (0.40) | DOT1LCKS1BSKP1SKP2CSNK1D | |
| SCHEMBL10078207 | 0.75 | CKS1B (0.34) | ADORA1CKS1BSKP1SKP2TLR7 | |
| SCHEMBL10078094 | 0.74 | MEN1 (0.34) | ADORA1CKS1BSKP1SKP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011114-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2012-01-26 | — | — | WO | disclosed |