Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983658 | 0.86 | HPGD (0.33) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL21322779 | 0.84 | — | — | |
| SCHEMBL19171189 | 0.84 | — | — | |
| SCHEMBL21322486 | 0.83 | — | — | |
| SCHEMBL18659982 | 0.82 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL14232236 | 0.79 | EPHX2 (0.39) | HTTSMN1; SMN2 | |
| SCHEMBL20056990 | 0.79 | HPGD (0.34) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL19828245 | 0.79 | — | — | |
| SCHEMBL18723291 | 0.78 | — | — | |
| SCHEMBL19450560 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014147-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011001052-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | WO | disclosed |