Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20261261 | 0.89 | POLB (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL20261185 | 0.88 | HPGD (0.32) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL20926869 | 0.87 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL18659982 | 0.85 | HPGD (0.36) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL24340751 | 0.83 | SMN1; SMN2 (0.41) | HPGDHTTSMN1; SMN2POLB | |
| SCHEMBL10086140 | 0.82 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL20926880 | 0.81 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL21727787 | 0.81 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL21498528 | 0.80 | — | — | |
| SCHEMBL10076956 | 0.79 | HPGD (0.31) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3308801-A1 | ANTIBODY DRUG CONJUGATE, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USES THEREOF | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2018-04-18 | — | — | EP | disclosed |