SCHEMBL10076980

SCHEMBL10076980

CC1CC(=O)c2cc(I)ccc2O1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.67
AR P10275 7/20 0.55
TDP1 Q9NUW8 2/20 0.43
BRD4 O60885 3/20 0.41
CREBBP Q92793 3/20 0.41
ABCB1 P08183 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
RAB9A P51151 3/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPT P10636 4/20 0.38
KDM4E B2RXH2 3/20 0.38
NPC1 O15118 2/20 0.38
GAA P10253 2/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 1/20 0.38
ALPL P05186 1/20 0.38
POLB P06746 1/20 0.38
ALPI P09923 1/20 0.38
ALPG P10696 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681000 0.81 PBRM1 (0.69) PBRM1TDP1BRD4CREBBPRAB9A
SCHEMBL3683723 0.81 PBRM1 (0.69) PBRM1TDP1BRD4CREBBPRAB9A
SCHEMBL1984847 0.80 PBRM1 (0.67) PBRM1TDP1BRD4CREBBPALDH1A1
SCHEMBL31015961 0.80 PBRM1 (1.00) PBRM1ARTDP1BRD4CREBBP
SCHEMBL2106757 0.80 PBRM1 (0.67) PBRM1TDP1BRD4CREBBPALDH1A1
SCHEMBL18013010 0.80 PBRM1 (1.00) PBRM1ARTDP1BRD4CREBBP
SCHEMBL68075 0.80 PBRM1 (0.67) PBRM1ARTDP1BRD4CREBBP
SCHEMBL4096551 0.78 PBRM1 (0.63) PBRM1ARTDP1BRD4CREBBP
SCHEMBL11381876 0.78 ABCB1 (0.66) PBRM1ARABCB1ABCG2RAB9A
SCHEMBL12264771 0.78 ABCB1 (0.66) PBRM1ARABCB1ABCG2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110253-B2 Ink composition FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20100285232-A1 PROCESS FOR PRODUCING AN OVERPRINT FUJIFILM CORPORATION (JP) 2010-11-11 US disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed