SCHEMBL68075

SCHEMBL68075

CC1CC(=O)c2cc(Cl)ccc2O1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.67
AR P10275 4/20 0.55
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
CYP19A1 P11511 1/20 0.42
BRD4 O60885 3/20 0.41
CREBBP Q92793 3/20 0.41
AKR1B1 P15121 2/20 0.41
ABCB1 P08183 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40
RAB9A P51151 2/20 0.39
KMT2A Q03164 2/20 0.39
MAOB P27338 1/20 0.38
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18013009 0.88 PBRM1 (0.60) PBRM1ARTDP1ALDH1A1MAPT
SCHEMBL9818829 0.87 PBRM1 (0.54) PBRM1ARTDP1ALDH1A1MAPT
SCHEMBL3681000 0.81 PBRM1 (0.69) PBRM1TDP1HTTCYP19A1BRD4
SCHEMBL3683723 0.81 PBRM1 (0.69) PBRM1TDP1HTTCYP19A1BRD4
SCHEMBL9818879 0.81 PBRM1 (0.58) PBRM1ARTDP1ALDH1A1MAPT
SCHEMBL9819094 0.81 PBRM1 (0.58) PBRM1ARTDP1ALDH1A1MAPT
SCHEMBL2106757 0.80 PBRM1 (0.67) PBRM1TDP1ALDH1A1MAPTCYP19A1
SCHEMBL1984847 0.80 PBRM1 (0.67) PBRM1TDP1ALDH1A1MAPTCYP19A1
SCHEMBL10076980 0.80 PBRM1 (0.67) PBRM1ARTDP1ALDH1A1MAPT
SCHEMBL31015961 0.80 PBRM1 (1.00) PBRM1ARTDP1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8147921-B2 Ink set for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-8147921-B2 Ink set for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8128843-B2 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8128843-B2 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-0230379-B1 CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS PFIZER INC. (US) 1991-04-03 EP disclosed
EP-0193855-B1 HYDANTOIN DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Eisai Co., Ltd. (JP) 1990-07-18 EP disclosed
US-4874869-A TREATMENT OF DIABETIC COMPLICATIONS, CATARACTS EISAI CO., LTD. (JP) 1989-10-17 US disclosed
US-4853410-A Hydroxyacetic acid derivatives for the treatment of diabetic complications PFIZER INC. (US) 1989-08-01 US disclosed
US-4780472-A Hydantoin derivatives for treating complications of diabetes EISAI CO., LTD. (JP) 1988-10-25 US disclosed
WO-1987004344-A1 HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS PFIZER INC. (US) 1987-07-30 WO disclosed
EP-0230379-A2 Chroman- and thiochroman-4-acetic acids useful in the treatment of diabetic complications PFIZER INC. (US) 1987-07-29 EP disclosed
EP-0193855-A1 Hydantoin derivatives, processes for preparing them and pharmaceutical compositions containing them Eisai Co., Ltd. (JP) 1986-09-10 EP disclosed
US-4540704-A Treating complications of diabetes mellitus with hydantoin derivatives EISAI CO., LTD. (JP) 1985-09-10 US disclosed
US-4261988-A ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY BAYER AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed