Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885942 | 0.91 | NR3C1 (0.42) | FFAR1MRGPRX4SLC22A12NR3C1S1PR3 | |
| SCHEMBL2889482 | 0.91 | FFAR1 (0.45) | FFAR1MRGPRX4SLC22A12FFAR4NR3C1 | |
| SCHEMBL223927 | 0.86 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL10076909 | 0.86 | FFAR1 (0.41) | FFAR1MRGPRX4SLC22A12CMKLR1 | |
| SCHEMBL2893994 | 0.82 | NR3C1 (0.42) | FFAR1MRGPRX4SLC22A12NR3C1S1PR3 | |
| SCHEMBL225912 | 0.80 | MRGPRX4 (0.48) | MRGPRX4SLC22A12AR | |
| SCHEMBL224879 | 0.79 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL224951 | 0.77 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL3920012 | 0.76 | MRGPRX4 (0.46) | MRGPRX4SLC22A12NR3C1AR | |
| SCHEMBL10077248 | 0.73 | FFAR1 (0.51) | FFAR1FFAR4CMKLR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |