Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 19/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008074 | 0.99 | HTR3A (0.50) | HTR3AKCNH2CYP2C19NPC1RAB9A | |
| SCHEMBL1008075 | 0.99 | HTR3A (0.50) | HTR3AKCNH2CYP2C19NPC1RAB9A | |
| Lithium Ion SCHEMBL1007740 | 0.91 | HTR3A (0.49) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1007163 | 0.90 | HTR3A (0.51) | HTR3AKCNH2 | |
| SCHEMBL1007165 | 0.90 | HTR3A (0.51) | HTR3AKCNH2 | |
| SCHEMBL1006017 | 0.83 | HTR3A (0.66) | HTR3AKCNH2 | |
| SCHEMBL1004970 | 0.83 | HTR3A (0.66) | HTR3AKCNH2 | |
| SCHEMBL1004971 | 0.83 | HTR3A (0.66) | HTR3AKCNH2 | |
| SCHEMBL1005124 | 0.82 | HTR3A (0.78) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1007050 | 0.82 | HTR3A (0.67) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863271-B2 | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |