⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660275 | 0.69 | — | — | |
| SCHEMBL466511 | 0.64 | — | — | |
| SCHEMBL15494266 | 0.64 | — | — | |
| SCHEMBL4169631 | 0.62 | — | — | |
| SCHEMBL4609598 | 0.62 | — | — | |
| SCHEMBL17265927 | 0.62 | — | — | |
| Ethylenediamine SCHEMBL8121893 | 0.61 | CA12 (0.47) | — | |
| Bromide SCHEMBL31050231 | 0.61 | — | — | |
| SCHEMBL18296056 | 0.59 | — | — | |
| SCHEMBL563507 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322785-A1 | ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY | MERCK SHARP & DOHME LLC (US) | 2023-10-12 | — | — | US | disclosed |
| EP-3555244-B1 | POLYMERS AS DIESEL FUEL ADDITIVES FOR DIRECT INJECTION DIESEL ENGINES | BASF SE (DE) | 2023-05-31 | — | — | EP | disclosed |
| WO-2021097240-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2021-05-20 | — | — | WO | disclosed |
| WO-2020154571-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20170313595-A1 | VANADIUM OXIDE FILM AND PROCESS FOR PRODUCING SAME | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2017-11-02 | — | — | US | disclosed |
| EP-3184527-A1 | 2,6-DIOXO,-2,3-DIHYDRO-1H-PURINE COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO THE ACTIVITY OF THE TRPA1 CHANNEL | Hydra Biosciences, Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9512442-B2 | Resistance gene and uses thereof | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) | 2016-12-06 | — | — | US | disclosed |
| US-9459213-B2 | Method of detecting nucleic acids, method of optically observing sample and fluorescent substance | SONY CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| US-20100160312-A1 | Substituted Pyridone Compounds and Methods of Use | AMGEN INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-7700607-B2 | Substituted pyridone compounds and methods of use | AMGEN INC. | 2010-04-20 | — | — | US | disclosed |
| US-20080249090-A1 | Substituted pyridone compounds and methods of use | AMGEN INC. (US) | 2008-10-09 | — | — | US | disclosed |
| US-7320714-B2 | High surface area porous aluminum electrode in electrolytic capacitors using solid freeform fabrication | INTEL CORPORATION (US) | 2008-01-22 | — | — | US | disclosed |
| US-20070259220-A1 | Hydrogen storage, distribution, and recovery system | REDMOND SCOTT D | 2007-11-08 | — | — | US | disclosed |
| US-20070224663-A1 | Identifying and characterizing novel human secreted proteins and their genes ; promotes vascularization; screening methods | HUMAN GENOME SCIENCES, INC. (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070185324-A1 | Nitrogen-containing bicyclic heteroaryl compounds and methods of use | AMGEN INC. | 2007-08-09 | — | — | US | disclosed |
| EP-1767148-A1 | MAGNETIC RESONANCE IMAGING DEVICE AND MAINTENANCE METHOD THEREFOR | Hitachi Medical Corporation (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | AMGEN INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070042439-A1 | Porphyrin compound containing biotinyl group and use thereof | RIKEN | 2007-02-22 | — | — | US | disclosed |