⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23791605 | 0.78 | — | — | |
| SCHEMBL15494266 | 0.75 | — | — | |
| SCHEMBL14220275 | 0.73 | — | — | |
| SCHEMBL13181704 | 0.71 | — | — | |
| SCHEMBL16277005 | 0.69 | — | — | |
| SCHEMBL17265927 | 0.62 | — | — | |
| SCHEMBL10078044 | 0.62 | — | — | |
| SCHEMBL278782 | 0.59 | — | — | |
| SCHEMBL11403495 | 0.59 | — | — | |
| SCHEMBL18296056 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331910-A1 | Mammalian and Bacterial Nitric Oxide Synthase Inhibitors | UNIV NORTHWESTERN (US) | 2020-10-22 | — | — | US | disclosed |
| US-10759791-B2 | Mammalian and bacterial nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2020-09-01 | — | — | US | disclosed |
| US-20170275278-A1 | Mammalian and Bacterial Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY (US) | 2017-09-28 | — | — | US | disclosed |
| EP-3215497-A2 | MAMMALIAN AND BACTERIAL NITRIC OXIDE SYNTHASE INHIBITORS | Northwestern University (US) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016073623-A2 | MAMMALIAN AND BACTERIAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2016-05-12 | — | — | WO | disclosed |
| EP-1950193-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20070111028-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1768199-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20060159957-A1 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |