Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290872 | 1.00 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3289368 | 1.00 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL3290012 | 0.88 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL5427322 | 0.85 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3291518 | 0.85 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL3290321 | 0.85 | P2RX7 (0.74) | P2RX7 | |
| SCHEMBL5308486 | 0.84 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL3292803 | 0.82 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL3288975 | 0.79 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL3287850 | 0.78 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217067-B2 | Antiinflammatory agents, antidepressants, analgesics, purinergic receptor antagonists; neurodegenerative diseases, spinal cord injuries; 1-(2,3-dichlorophenyl)-N-[(2-methylphenyl)methyl]-1H-tetraazol-5-amine | ABBOTT LABORATORIES (US) | 2012-07-10 | — | — | US | claimed |