Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12208421 | 0.81 | MEN1 (0.42) | GRIA4HPGDMAOAMAOBKDM1A | |
| SCHEMBL27945836 | 0.76 | SLC18A3 (0.49) | GRIA4HPGDHRH3MAOAMAOB | |
| SCHEMBL16830132 | 0.75 | MEN1 (0.46) | GRIA4MAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL16830133 | 0.75 | MEN1 (0.46) | GRIA4MAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL325104 | 0.75 | MEN1 (0.46) | GRIA4MAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL16830124 | 0.75 | MEN1 (0.46) | GRIA4MAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL16830122 | 0.75 | MEN1 (0.46) | GRIA4MAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL446482 | 0.72 | MAOB (0.48) | HPGDMAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL16762126 | 0.72 | MAOB (0.48) | HPGDMAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL446481 | 0.72 | MAOB (0.48) | HPGDMAOAMAOBKDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044719-A1 | NORBORNANE-BASED PAC BALLAST AND POSITIVE-TONE PHOTOSENSITIVE RESIN COMPOSITION ENCOMPASSING THE PAC | PROMERUS LLC (US) | 2012-04-05 | — | — | WO | disclosed |