Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106626 | 0.79 | MPL (0.44) | MPL | |
| SCHEMBL1106630 | 0.78 | MPL (0.47) | MPL | |
| SCHEMBL1102188 | 0.70 | MPL (0.83) | MPL | |
| SCHEMBL1090226 | 0.69 | MPL (0.63) | MPL | |
| SCHEMBL1102185 | 0.68 | MPL (0.84) | MPL | |
| SCHEMBL1102105 | 0.68 | MPL (0.64) | MPL | |
| SCHEMBL1102194 | 0.68 | MPL (0.84) | MPL | |
| SCHEMBL1102197 | 0.66 | MPL (0.48) | MPL | |
| SCHEMBL1102210 | 0.66 | MPL (0.46) | MPL | |
| SCHEMBL1102222 | 0.66 | MPL (0.49) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153671-B2 | Heterotetracyclic compounds as TPO mimetics | IRM LLC (BM) | 2012-04-10 | — | — | US | disclosed |