Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102156 | 0.91 | MPL (1.00) | MPL | |
| SCHEMBL14641112 | 0.88 | MPL (0.73) | MPL | |
| SCHEMBL1102203 | 0.88 | MPL (0.73) | MPL | |
| SCHEMBL1091360 | 0.85 | MPL (0.90) | MPL | |
| SCHEMBL1102185 | 0.84 | MPL (0.84) | MPL | |
| SCHEMBL1102187 | 0.84 | MPL (0.68) | MPL | |
| SCHEMBL1102227 | 0.82 | MPL (0.66) | MPL | |
| SCHEMBL1102184 | 0.82 | MPL (0.68) | MPL | |
| SCHEMBL1091888 | 0.82 | MPL (0.89) | MPL | |
| SCHEMBL1102178 | 0.81 | MPL (0.67) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153671-B2 | Heterotetracyclic compounds as TPO mimetics | IRM LLC (BM) | 2012-04-10 | — | — | US | disclosed |