Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290855 | 0.79 | TLR8 (0.54) | ALDH1A1KDM4ELMNACYP3A4HIF1A | |
| SCHEMBL13536956 | 0.78 | PKM (0.39) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL6289604 | 0.77 | TLR8 (0.55) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL15045025 | 0.77 | MGAM (0.51) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL11054926 | 0.77 | TP53 (0.54) | TSHRRARB | |
| SCHEMBL10081274 | 0.76 | GRIN2D (0.68) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL28065707 | 0.76 | TLR8 (0.53) | ALDH1A1KDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL23674307 | 0.76 | OXER1 (0.45) | ALDH1A1KAT8PPARATLR8PPARG | |
| SCHEMBL9295912 | 0.75 | MGAM (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7331987 | 0.75 | GRIN2D (0.67) | ALDH1A1MEN1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |