Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080500 | 1.00 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2CPLA2G2DRARB | |
| SCHEMBL10080499 | 0.99 | GRIN2D (0.54) | GRIN2DGRIN2AGRIN2CPLA2G2DRARB | |
| SCHEMBL10080478 | 0.95 | GRIN2D (0.55) | GRIN2DGRIN2AGRIN2CPLA2G2DRARB | |
| SCHEMBL10080753 | 0.89 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2CPLA2G2DALDH1A1 | |
| SCHEMBL10080752 | 0.84 | GRIN2D (0.62) | GRIN2DGRIN2AGRIN2CALDH1A1MEN1 | |
| SCHEMBL29898231 | 0.83 | GRIN2D (0.56) | GRIN2DGRIN2AGRIN2CRARBALDH1A1 | |
| SCHEMBL10080467 | 0.83 | GRIN2D (0.56) | GRIN2DGRIN2AGRIN2CRARBALDH1A1 | |
| SCHEMBL27760654 | 0.82 | MAPT (0.48) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10080492 | 0.81 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2CALDH1A1 | |
| SCHEMBL10080754 | 0.80 | GRIN2D (0.64) | GRIN2DGRIN2AGRIN2CPLA2G2DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |