Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080753 | 0.89 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080754 | 0.89 | GRIN2D (0.64) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080478 | 0.87 | GRIN2D (0.55) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080499 | 0.86 | GRIN2D (0.54) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080500 | 0.84 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080490 | 0.84 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080492 | 0.83 | GRIN2D (0.57) | GRIN2DGRIN2AGRIN2CALDH1A1KDM4E | |
| SCHEMBL10080515 | 0.82 | GRIN2D (0.56) | GRIN2DGRIN2AGRIN2CACE2CYP1A2 | |
| SCHEMBL10080751 | 0.82 | GRIN2D (0.52) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD | |
| SCHEMBL10080755 | 0.81 | CYP4F2 (0.52) | GRIN2DGRIN2AGRIN2CALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |