Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007119 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL8984382 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL6422109 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL2871485 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL8984468 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL2867823 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL5508985 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL830483 | 1.00 | MAPT (0.59) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL712393 | 0.98 | MAPT (0.56) | MAPTRXFP1EPHX2HDAC3HDAC4 | |
| SCHEMBL31482293 | 0.97 | MAPT (0.56) | MAPTRXFP1EPHX2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025134071-A1 | MALIC AND GLUTARIC ACID BASED IONIZABLE LIPIDS | SANOFI (FR) | 2025-06-26 | — | — | WO | disclosed |
| US-11420933-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2022-08-23 | — | — | US | disclosed |
| EP-3623361-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |
| EP-3623361-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |
| US-20210078936-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-03-18 | — | — | US | disclosed |
| US-20210078936-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-03-18 | — | — | US | disclosed |
| US-10906867-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| US-10906867-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2021-02-02 | — | — | US | disclosed |
| EP-3623361-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2020-03-18 | — | — | EP | disclosed |
| EP-3083556-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2019-12-25 | — | — | EP | disclosed |
| US-20090270505-A1 | 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2009-10-29 | — | — | US | disclosed |
| EP-0872467-B1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEM CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6048989-A | PARASITICIDES AND ANTIBROTOZOA AGENTS | WASHINGTON UNIVERSITY (US) | 2000-04-11 | — | — | US | disclosed |
| US-6025511-A | A MYRISTIC ACID SELECTED ANALOGS FOR INHIBITING THE BIOSYNTHESIS OF THE GLYCOSYL PHOSPHATIDYLINOSITOL (GPI) ANCHOR OF THE PARASITE | WASHINGTON UNIVERSITY (US) | 2000-02-15 | — | — | US | disclosed |
| US-6001869-A | CONTACTING THE PARASITE WITH 2-THIENYL-UNDECENOIC ACID/10-/ | WASHINGTON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5998642-A | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5886214-A | CATALYTIC ASYMMETRIC HYDROGENATION OF ENOL ESTERS BEARING A VINYLLIC OR AN ACETYLENIC SUBSTITUENT BY USING A CHIRAL RHODIUM(I) HYDROGENATION CATALYST PREPARED FROM A SUITABLE RHODIUM SALT AND AN OPTICALLY PURE PHOSPHINE LIGAND | EASTMAN CHEMICAL COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| EP-0872467-A1 | Process for the production of chiral unsaturated alcohols in high optical purity | EASTMAN CHEMICAL COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5760259-A | MYRISTIC ACID DERIVATIVES CAPABLE OF INHIBITING BIOSYNTHESIS OF PARASITE'S ANCHORING GROUP | WASHINGTON UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270505-A1 | 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES | CPT1B, CPT1A, CPT2 | MAPT 935/4885RXFP1 2945/4885EPHX2 2708/4885 |
| US-20210078936-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LPAR1, LPAR4, LIPA | MAPT 3628/4885RXFP1 280/4885EPHX2 1165/4885 |
| US-11420933-B2 | Lipids and lipid compositions for the delivery of active agents | LPAR1, LPAR4, LIPA | MAPT 3628/4885RXFP1 280/4885EPHX2 1165/4885 |
| US-10906867-B2 | Lipids and lipid compositions for the delivery of active agents | LPAR1, LPAR4, LIPA | MAPT 3628/4885RXFP1 280/4885EPHX2 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.