SCHEMBL830483

SCHEMBL830483

O=C(O)CCCCCOCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
EPHX2 P34913 2/20 0.57
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC7 Q8WUI4 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC10 Q969S8 2/20 0.53
HDAC11 Q96DB2 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
HDAC9 Q9UKV0 2/20 0.53
HDAC5 Q9UQL6 2/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53
SLC6A3 Q01959 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2871485 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL8984468 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL8984382 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL6422109 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL2867823 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL1008067 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL1007119 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL5508985 1.00 MAPT (0.59) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL712393 0.98 MAPT (0.56) MAPTRXFP1EPHX2HDAC3HDAC4
SCHEMBL31482293 0.97 MAPT (0.56) MAPTRXFP1EPHX2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025134071-A1 MALIC AND GLUTARIC ACID BASED IONIZABLE LIPIDS SANOFI (FR) 2025-06-26 WO disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed
US-20240092819-A1 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR SANOFI SA (FR) 2024-03-21 US disclosed
EP-4232455-A2 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR Sanofi (FR) 2023-08-30 EP disclosed
CN-116368146-A Novel ligands for asialoglycoprotein receptors 赛诺菲 2023-06-30 CN disclosed
WO-2022084331-A2 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR SANOFI (FR) 2022-04-28 WO disclosed
US-10866230-B2 Fiber coated nanopores TRUSTEES OF BOSTON UNIVERSITY (US) 2020-12-15 US disclosed
US-10851367-B2 Tissue-specific genome engineering using CRISPR-Cas9 PFIZER INC. (US) 2020-12-01 US disclosed
US-10851367-B2 Tissue-specific genome engineering using CRISPR-Cas9 PFIZER INC. (US) 2020-12-01 US disclosed
EP-1021423-A1 MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNF$g(a) SECRETION Abbott Laboratories (US) 2000-07-26 EP disclosed
EP-0964851-A1 C-TERMINAL KETONE HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFA SECRETION Abbott Laboratories (US) 1999-12-22 EP disclosed
US-5985911-A COMBATTING DISEASE STATES INVOLVING TISSUE DEGENERATIVE PROCESSES I.E, RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR ABBOTT LABORATORIES (US) 1999-11-16 US disclosed
US-5952320-A USEFUL IN THE TREATMENT OF DISEASES IN WHICH MATRIX METALLOPROTEINASE PLAY A ROLE; MATRIX METALLOPROTEINASE INHIBITING COMPOSITIONS ABBOTT LABORATORIES (US) 1999-09-14 US disclosed
WO-1998030541-A1 C-TERMINAL KETONE HYDROXAMIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFA SECRETION ABBOTT LABORATORIES (US) 1998-07-16 WO disclosed
WO-1998030551-A1 MACROCYCLIC INHIBITORS OF MATRIX METALLOPROTEINASES AND TNFα SECRETION ABBOTT LABORATORIES (US) 1998-07-16 WO disclosed
US-5618844-A MATRIX METALLOPROTEINASE INHIBITOR SANOFI S.A. (FR) 1997-04-08 US disclosed
US-5514716-A MATRIX METALLOPROTEINASE INHIBITORS, ANTIARTHRITIC STERLING WINTHROP, INC. (US) 1996-05-07 US disclosed
US-5153214-A Treating cardiovascular disorders CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
EP-0493324-A1 Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS MAPT 2060/4885RXFP1 4587/4885EPHX2 4386/4885
US-10851367-B2 Tissue-specific genome engineering using CRISPR-Cas9 ASGR1, LDLR, HAVCR2 MAPT 3945/4885RXFP1 1765/4885EPHX2 1793/4885
US-20240092819-A1 NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR ASGR1, HAVCR2, SIGLEC7 MAPT 4869/4885RXFP1 1114/4885EPHX2 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.