SCHEMBL10080729

SCHEMBL10080729

C=CC(=O)NCCCCC(=O)NCC

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.62
ZDHHC2 Q9UIJ5 1/20 0.62
FAAH O00519 3/20 0.53
EPHX2 P34913 4/20 0.46
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TGM2 P21980 2/20 0.43
CASP2 P42575 1/20 0.43
SLC6A5 Q9Y345 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NAAA Q02083 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2611992 0.98 ZDHHC20 (0.66) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL28421702 0.95 ZDHHC20 (0.59) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24760845 0.87 ZDHHC20 (0.63) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL10080737 0.87 ZDHHC20 (0.53) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24760721 0.87 ZDHHC20 (0.58) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24762332 0.87 ZDHHC20 (0.58) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24652898 0.86 ZDHHC20 (0.74) ZDHHC20ZDHHC2FAAHEPHX2CASP2
SCHEMBL24761188 0.85 ZDHHC20 (0.61) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24761182 0.85 ZDHHC20 (0.61) ZDHHC20ZDHHC2FAAHEPHX2TSHR
SCHEMBL24762268 0.85 ZDHHC20 (0.60) ZDHHC20ZDHHC2FAAHEPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 ZDHHC20 1156/4885ZDHHC2 565/4885FAAH 3150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.