ZDHHC20 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL137967	0.72	4/20
SCHEMBL252541	0.72	4/20
SCHEMBL372568	0.72	4/20
SCHEMBL372601	0.72	4/20
SCHEMBL372802	0.72	4/20
SCHEMBL345353	0.61	4/20
SCHEMBL301435	0.57	4/20
SCHEMBL372729	0.57	4/20
SCHEMBL25793	1.00	3/20
SCHEMBL36870	1.00	3/20
SCHEMBL220516	1.00	3/20
SCHEMBL232770	1.00	3/20
SCHEMBL252114	1.00	3/20
SCHEMBL346798	1.00	3/20
SCHEMBL36287	0.50	3/20
SCHEMBL85840	0.44	3/20
SCHEMBL108156	0.43	3/20
SCHEMBL36276	0.56	2/20
SCHEMBL114687	0.54	2/20
SCHEMBL379417	0.54	2/20

Clinical trials — most relevant to ZDHHC20 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cystagon to Treat Infantile Neuronal Ceroid Lipofuscinosis	PHASE4	COMPLETED
Cholic Acid for Hepatic Steatosis in Lipodystrophy	PHASE2	COMPLETED
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension	PHASE2	NOT_YET_RECRUITING
Choline Effects - Pre-symptomatic AD	PHASE1	COMPLETED
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism	EARLY_PHASE1	UNKNOWN
Targeting zDHHC Enzymes to Counteract Alzheimer's Disease	nan	NOT_YET_RECRUITING
Target of Suv420h1/2 in Hepatocytes	nan	RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Gene Expression in Obesity and Insulin Resistance	nan	COMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Genomic Dissection of a QTL Affecting the Lipid Profile	nan	WITHDRAWN
Genes Involved in Lipid Disorders	nan	COMPLETED
Genetic Origin of Lipid Disorders	nan	UNKNOWN
Familial Partial Lipodystrophy Study	nan	COMPLETED
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children	nan	WITHDRAWN
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
Apolipoprotein Polymorphisms and Risk of Coronary Heart Disease	nan	COMPLETED
Study of Protein Translocation in Patients With Beta-Oxidation Disorders	nan	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Identification and Metabolic Characterization of a Cohort of Human Subjects With Mutations in PRDM-16	nan	COMPLETED
Genetic and Environmental Determinants of Triglycerides (GOLDN)	nan	COMPLETED
Genetic and Metabolic Disease in Children	nan	RECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy	nan	COMPLETED
Gene Expression and Inflammation in Overweight Subjects	nan	COMPLETED
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study	nan	COMPLETED
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a ZDHHC20 binder may also engage these)

Protein	Name	Similarity
Q0VC89	—	1.000	Q0VC89 →
Q5Y5T1	—	1.000	Q5Y5T1 →
Q6FW70	—	1.000	Q6FW70 →
Q96MV8	—	1.000	Q96MV8 →
F1QXD3	—	1.000	F1QXD3 →
Q8I0G4	—	1.000	Q8I0G4 →
Q94C49	—	1.000	Q94C49 →
Q6BMV2	—	1.000	Q6BMV2 →
Q6CUB5	—	1.000	Q6CUB5 →
Q8VYP5	—	1.000	Q8VYP5 →
Q6CQB5	—	1.000	Q6CQB5 →
E7F587	—	1.000	E7F587 →
Q03289	—	0.999	Q03289 →
P0C7U3	—	0.999	P0C7U3 →
Q5BLG4	—	0.999	Q5BLG4 →
Q6CPU8	—	0.999	Q6CPU8 →
Q14AK4	—	0.998	Q14AK4 →
B3DN87	—	0.997	B3DN87 →
A0A0R4IF99	—	0.997	A0A0R4IF99 →
O74384	—	0.997	O74384 →
Q5RB84	—	0.997	Q5RB84 →
Q5REH2	—	0.997	Q5REH2 →
F1Q7H8	—	0.997	F1Q7H8 →
Q5M757	—	0.997	Q5M757 →
F1QGD2	—	0.997	F1QGD2 →
Q7XA86	—	0.997	Q7XA86 →
Q9CPV7	—	0.997	Q9CPV7 →
Q9M1K5	—	0.997	Q9M1K5 →
Q9SB58	—	0.996	Q9SB58 →
Q93VV0	—	0.996	Q93VV0 →