SCHEMBL10081539

SCHEMBL10081539

CC(CCCCCCCCC#CCCCCCCCC(=O)O)CCCCCCCCC#CCCCCCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN7 P35236 5/20 0.63
▸ HMGCR P04035 4/20 0.63
▸ RECQL P46063 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ MAPT P10636 2/20 0.50
▸ EPHX2 P34913 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ USP2 O75604 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ ALOX12 P18054 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ MCL1 Q07820 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ CYP1A2 P05177 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5930428 0.89 PTPN7 (0.63) PTPN7HMGCRRECQLTDP1MAPT
SCHEMBL3137343 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9405656 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9405657 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL8054929 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL19940379 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9405636 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL3829825 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL5710414 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9405592 0.88 TSHR (0.60) TDP1MEN1ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2023-08-17 — — US disclosed
US-11679158-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2023-06-20 — — US disclosed
US-20180065920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2018-03-08 — — US disclosed
US-9682922-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2017-06-20 — — US disclosed
US-20160009637-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2016-01-14 — — US disclosed
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS BANK OF AMERICA, N.A. 2015-10-01 — — US disclosed
US-9061063-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-06-23 — — US disclosed
US-9012498-B2 Biodegradable lipids for the delivery of active agents ALNYLAM PHARMACEUTICALS, INC. (US) 2015-04-21 — — US disclosed
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2013-08-01 — — US disclosed
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120027803-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB PTPN7 4356/4885HMGCR 57/4885RECQL 1649/4885
US-20160009637-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB PTPN7 4356/4885HMGCR 57/4885RECQL 1649/4885
US-20130195920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP PTPN7 4257/4885HMGCR 77/4885RECQL 1613/4885
US-20150273068-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP PTPN7 4257/4885HMGCR 77/4885RECQL 1613/4885
US-11679158-B2 Biodegradable lipids for the delivery of active agents LIPA, APOB, CETP PTPN7 4257/4885HMGCR 77/4885RECQL 1613/4885
US-20230256098-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, APOB, CETP PTPN7 4257/4885HMGCR 77/4885RECQL 1613/4885
US-20180065920-A1 BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, CETP, APOB PTPN7 4356/4885HMGCR 57/4885RECQL 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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