SCHEMBL10082102

SCHEMBL10082102

Cc1c2ccnc(C)c2c(C)c2c1[nH]c1ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.62
GABRG2 P18507 5/20 0.62
GABRB3 P28472 5/20 0.62
GABRA5 P31644 5/20 0.62
GABRA3 P34903 5/20 0.62
GABRA2 P47869 5/20 0.62
MEN1 O00255 4/20 0.62
MAPT P10636 4/20 0.62
KMT2A Q03164 4/20 0.62
KDM4E B2RXH2 4/20 0.62
GABRP O00591 4/20 0.62
GABRD O14764 4/20 0.62
GABRB1 P18505 4/20 0.62
GABRB2 P47870 4/20 0.62
GABRA4 P48169 4/20 0.62
GABRE P78334 4/20 0.62
GABRA6 Q16445 4/20 0.62
GABRG1 Q8N1C3 4/20 0.62
GABRG3 Q99928 4/20 0.62
GABRQ Q9UN88 4/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17633451 0.85 MEN1 (0.58) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL27442273 0.81 MEN1 (0.50) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL13100676 0.80 KDM4E (0.59) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL32690150 0.80 MEN1 (0.55) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL4342832 0.80 KDM4E (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15413439 0.80 MEN1 (0.55) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL17633446 0.79 MEN1 (0.51) GABRA1GABRG2GABRB3GABRA5GABRA3
Hydrochloric Acid SCHEMBL15413335 0.79 MEN1 (0.54) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15195212 0.78 MEN1 (0.73) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL554573 0.78 MAPT (0.64) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed