Sugi Predict

Sugi Predict / Compounds / SCHEMBL554573

SCHEMBL554573

SCHEMBL554573

Cc1c2[nH]c3ccccc3c2c(C)c2[nH]c3ccccc3c12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.64
▸ MEN1 O00255 5/20 0.64
▸ KMT2A Q03164 5/20 0.64
▸ KDM4E B2RXH2 3/20 0.62
▸ ALDH1A1 P00352 3/20 0.62
▸ HSD17B10 Q99714 3/20 0.62
▸ MAPK1 P28482 3/20 0.62
▸ NPSR1 Q6W5P4 3/20 0.62
▸ LMNA P02545 2/20 0.62
▸ CYP1A2 P05177 2/20 0.62
▸ CYP3A4 P08684 2/20 0.62
▸ CYP2D6 P10635 2/20 0.62
▸ HPGD P15428 2/20 0.62
▸ TSHR P16473 2/20 0.62
▸ NFKB1 P19838 2/20 0.62
▸ APEX1 P27695 2/20 0.62
▸ BLM P54132 2/20 0.62
▸ NPC1 O15118 1/20 0.62
▸ GMNN O75496 1/20 0.62
▸ NR3C1 P04150 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6484501 0.91 MAPT (0.60) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15195212 0.91 MEN1 (0.73) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL18906311 0.90 PARP1 (0.58) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL23861154 0.89 MEN1 (0.53) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL28932368 0.84 MEN1 (0.56) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL22044246 0.81 MAPT (0.59) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL16432861 0.81 PARP1 (0.54) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL9622618 0.80 KDM4E (0.50) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL9623275 0.80 PARP1 (0.57) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL4733891 0.80 MEN1 (0.55) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184391-B2 Compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION (US) 2015-11-10 — — US disclosed
US-20140148567-A1 COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE XEROX CORPORATION (US) 2014-05-29 — — US disclosed
US-20140088313-A1 SUBSTITUTED INDOLOCARBAZOLES XEROX CORPORATION (US) 2014-03-27 — — US disclosed
US-8673959-B2 Polymer having indolocarbazole moiety and divalent linkage XEROX CORPORATION (US) 2014-03-18 — — US disclosed
US-8609867-B2 Substituted indolocarbazoles XEROX CORPORATION (US) 2013-12-17 — — US disclosed
EP-1671998-B1 Process to form compound with indolocarbazole moieties XEROX CORP (US) 2013-02-20 — — EP disclosed
US-20120157689-A1 SUBSTITUTED INDOLOCARBAZOLES XEROX CORPORATION (US) 2012-06-21 — — US disclosed
US-8110690-B2 Substituted indolocarbazoles XEROX CORPORATION (US) 2012-02-07 — — US disclosed
US-8003807-B2 organic thin film transistor with a semiconductor layer including the small molecule having didodecylindolo[3,2-b]carbazole groups XEROX CORPORATION (US) 2011-08-23 — — US disclosed
US-7868186-B2 Device containing polymer having indolocarbazole- repeat unit and divalent linkage XEROX CORPORATION (US) 2011-01-11 — — US disclosed
US-20070112167-A1 Device containing compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION 2007-05-17 — — US disclosed
US-20070112172-A1 Compound having indolocarbazole moiety and divalent linkage XEROX CORPORATION 2007-05-17 — — US disclosed
US-7173140-B2 Process to form compound with indolocarbazole moieties XEROX CORPORATION (US) 2007-02-06 — — US disclosed
US-20060214155-A1 Compound with indolocarbazole moieties and devices containing such compound XEROX CORPORATION 2006-09-28 — — US disclosed
EP-1672713-A1 Compound with indolocarbazole moieties and electronic devices containing such compound Xerox Corporation (US) 2006-06-21 — — EP disclosed
EP-1671998-A2 Process to form compound with indolocarbazole moieties Xerox Corporation (US) 2006-06-21 — — EP disclosed
US-20060124923-A1 Thin film transistors including indolocarbazoles XEROX CORPORATION 2006-06-15 — — US disclosed
US-20060124921-A1 Compound with indolocarbazole moieties and devices containing such compound XEROX CORPORATION (US) 2006-06-15 — — US disclosed
US-20060125009-A1 Thin film transistors including indolocarbazoles XEROX CORPORATION 2006-06-15 — — US disclosed
US-20060128969-A1 Process to form compound with indolocarbazole moieties XEROX CORPORATION 2006-06-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070112172-A1 Compound having indolocarbazole moiety and divalent linkage INMT, IDO2, GRIN2C MAPT 163/4885MEN1 1019/4885KMT2A 852/4885
US-20060128969-A1 Process to form compound with indolocarbazole moieties INMT, CYP3A4, PLK1 MAPT 77/4885MEN1 797/4885KMT2A 3095/4885
US-20060214155-A1 Compound with indolocarbazole moieties and devices containing such compound BRD4, INO80C, BICRA MAPT 377/4885MEN1 1804/4885KMT2A 1993/4885
US-20060124921-A1 Compound with indolocarbazole moieties and devices containing such compound BRD4, INO80C, BICRA MAPT 377/4885MEN1 1804/4885KMT2A 1993/4885
US-20120157689-A1 SUBSTITUTED INDOLOCARBAZOLES HTR3C, HTR3A, AANAT MAPT 196/4885MEN1 1612/4885KMT2A 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.