Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082469 | 0.88 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CCYP19A1 | |
| SCHEMBL14393065 | 0.84 | PDE4D (0.35) | PDE4DPDE4APDE4BPDE4CMAPT | |
| SCHEMBL561469 | 0.84 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4CKCNMA1 | |
| SCHEMBL693150 | 0.82 | GPR35 (0.50) | PDE4DPDE4APDE4BPDE4CMAPT | |
| SCHEMBL1166903 | 0.81 | PDE4D (0.45) | PDE4DPDE4APDE4BPDE4CKCNMA1 | |
| SCHEMBL13079806 | 0.80 | CYP19A1 (0.39) | PDE4DCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL1166603 | 0.79 | KDM4A (0.43) | PDE4DPDE4APDE4BPDE4CKCNMA1 | |
| SCHEMBL8126843 | 0.77 | EP300 (0.41) | PDE4DCYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8136635 | 0.75 | PDE4D (0.37) | PDE4DPDE4APDE4BPDE4CCYP19A1 | |
| SCHEMBL2744039 | 0.75 | PDE10A (0.38) | PDE4DPDE4APDE4BPDE4CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087596-A1 | COMBINATIONS FOR TREATING HCV | GILEAD SCIENCES, INC. (US) | 2012-06-28 | — | — | WO | disclosed |