SCHEMBL10083534

SCHEMBL10083534

Cc1ccc2c(c1)C(=O)c1cc(N=Nc3c(O)c(C(=O)Nc4ccccc4Cl)cc4ccccc34)ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F12 P00748 1/20 0.46
▸ NQO2 P16083 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ NPC1 O15118 4/20 0.42
▸ POLB P06746 3/20 0.41
▸ CASP3 P42574 2/20 0.41
▸ ATM Q13315 1/20 0.41
▸ SENP8 Q96LD8 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41
▸ SENP6 Q9GZR1 1/20 0.41
▸ MEN1 O00255 4/20 0.41
▸ KMT2A Q03164 4/20 0.41
▸ MAPT P10636 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.39
▸ IDO1 P14902 1/20 0.39
▸ MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029442 0.94 NQO2 (0.49) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL713606 0.94 NQO2 (0.49) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL4392708 0.92 NQO2 (0.48) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL85619 0.92 NQO2 (0.48) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL12382300 0.91 NQO2 (0.43) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL12228818 0.91 NQO2 (0.49) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL14092687 0.90 NQO2 (0.57) NQO2ALDH1A1CYP1A2RAB9ANPC1
SCHEMBL13373965 0.89 NQO2 (0.45) NQO2ALDH1A1CYP1A2RAB9ANPC1
SCHEMBL14264272 0.89 NQO2 (0.48) F12NQO2ALDH1A1CYP1A2RAB9A
SCHEMBL14817399 0.89 NQO2 (0.44) F12NQO2ALDH1A1CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8989645-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2015-03-24 — — US disclosed
US-20130259552-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2013-10-03 — — US disclosed
US-8114563-B2 Forming photosensitive layer on electroconductive substrate wherein the crosslinked surface layer has a surface roughness (Ra) not greater than 0.2 mu m and a peel strength not less than 0.2 N/mm; durability, stable electrical properties, good cleanability, and producing high-quality images RICOH COMPANY, LIMITED (JP) 2012-02-14 — — US disclosed
US-7858278-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2010-12-28 — — US disclosed
US-7858278-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY LIMITED (JP) 2010-12-28 — — US disclosed
US-7691931-B2 Organic-inorganic hybrid material and method of preparing the organic-inorganic hybrid material, and electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method using the organic-inorganic hybrid material RICOH COMPANY LTD. (JP) 2010-04-06 — — US disclosed
US-7341814-B2 Electrophotographic photoconductor, preparation method thereof, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2008-03-11 — — US disclosed
US-7341814-B2 Electrophotographic photoconductor, preparation method thereof, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2008-03-11 — — US disclosed
US-20080038649-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR RICOH COMPANY, LIMITED (JP) 2008-02-14 — — US disclosed
US-20070269729-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-11-22 — — US disclosed
US-20070269729-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2007-11-22 — — US disclosed
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