SCHEMBL85619

SCHEMBL85619

Cc1cccc(NC(=O)c2cc3ccccc3c(N=Nc3ccc4c(c3)C(=O)c3cc(N=Nc5c(O)c(C(=O)Nc6ccccc6Cl)cc6ccccc56)ccc3-4)c2O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NQO2 P16083 1/20 0.48
▸ GAA P10253 2/20 0.42
▸ PTGES O14684 1/20 0.42
▸ F12 P00748 2/20 0.41
▸ NPC1 O15118 3/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ MAOB P27338 2/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ MAOA P21397 1/20 0.41
▸ KCNK3 O14649 1/20 0.40
▸ KCNK9 Q9NPC2 1/20 0.40
▸ MEN1 O00255 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ MAPT P10636 3/20 0.39
▸ CRHBP P24387 1/20 0.39
▸ CRHR2 Q13324 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ POLB P06746 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4392708 1.00 NQO2 (0.48) NQO2GAAPTGESF12NPC1
SCHEMBL14264272 0.97 NQO2 (0.48) NQO2GAAPTGESF12NPC1
SCHEMBL12363886 0.93 NQO2 (0.44) NQO2GAAPTGESF12NPC1
SCHEMBL11948158 0.93 NQO2 (0.46) NQO2GAAPTGESF12NPC1
SCHEMBL10083534 0.92 F12 (0.46) NQO2F12NPC1RAB9AMAOB
SCHEMBL14092687 0.92 NQO2 (0.57) NQO2GAAPTGESNPC1RAB9A
SCHEMBL15449666 0.91 NQO2 (0.47) NQO2GAAPTGESF12NPC1
SCHEMBL13244376 0.91 NQO2 (0.53) NQO2GAAF12NPC1RAB9A
SCHEMBL713606 0.91 NQO2 (0.49) NQO2PTGESF12NPC1RAB9A
SCHEMBL5029442 0.91 NQO2 (0.49) NQO2PTGESF12NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9864322-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2018-01-09 — — US disclosed
US-20160363886-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2016-12-15 — — US disclosed
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 — — US disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 — — US disclosed
US-9081353-B2 Cleaner, and process cartridge and image forming apparatus using the cleaner RICOH COMPANY, LTD. (JP) 2015-07-14 — — US disclosed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 — — US disclosed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 — — US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 — — US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 — — US disclosed
US-8912348-B2 Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound RICOH COMPANY, LTD. (JP) 2014-12-16 — — US disclosed
US-20070154825-A1 Electrophotographic photoreceptor, method of image formation, image formation apparatus and process cartridge for image formation apparatus RICOH COMPANY, LTD. (JP) 2007-07-05 — — US disclosed
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND RICOH COMPANY, LTD. (JP) 2007-06-07 — — US disclosed
US-20070122724-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING PROCESS, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE FOR AN IMAGE FORMING APPARATUS USING THE SAME SUZUKI TETSURO 2007-05-31 — — US disclosed
US-20070065739-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-22 — — US disclosed
US-7183435-B2 Hexasubstituted with a tertiary amino phenyl groups; stability, rapid response and good transportability; electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-27 — — US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 — — US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 — — US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 — — US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 — — US disclosed
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070128530-A1 TETRAHYDROXY COMPOUND, METHOD FOR PREPARING THE TETRAHYDROXY COMPOUND, AND PHOTORECEPTOR USING THE TETRAHYDROXY COMPOUND ALDH1A2, SLC9B2, SLC18A2 NQO2 1107/4885GAA 4598/4885PTGES 1733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback