Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 1.00 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.68 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.39 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.39 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073526 | 1.00 | FASN (1.00) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL16551923 | 0.91 | FASN (0.83) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL16551963 | 0.91 | FASN (0.83) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL15012876 | 0.89 | FASN (0.81) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL15012874 | 0.89 | FASN (0.81) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL28541028 | 0.89 | FASN (0.79) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL17973346 | 0.85 | FASN (0.73) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL31138044 | 0.85 | FASN (0.73) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL16201812 | 0.82 | FASN (0.69) | FASNCTRB1PLA2G6PLA2G4AF2 | |
| SCHEMBL16551934 | 0.81 | FASN (0.68) | FASNCTRB1PLA2G6PLA2G4ALYPLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | FASN, COASY, FADS1 | FASN 1/4885CTRB1 1071/4885PLA2G6 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.