Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.71 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 6/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666301 | 0.92 | CASP2 (0.59) | EPHX2SLC6A5KDM4EFAAHMEN1 | |
| SCHEMBL47703 | 0.92 | CASP2 (0.59) | EPHX2SLC6A5KDM4EFAAHMEN1 | |
| SCHEMBL10088131 | 0.90 | CASP2 (0.56) | EPHX2SLC6A5CNR1HPGDFAAH | |
| SCHEMBL17273870 | 0.88 | EPHX2 (0.65) | EPHX2 | |
| SCHEMBL10802572 | 0.88 | EPHX2 (0.72) | EPHX2SLC6A5KDM4ECNR1LPAR1 | |
| SCHEMBL1999120 | 0.88 | EPHX2 (0.72) | EPHX2SLC6A5KDM4ECNR1LPAR1 | |
| SCHEMBL1999124 | 0.88 | EPHX2 (0.72) | EPHX2SLC6A5KDM4ECNR1LPAR1 | |
| SCHEMBL25334864 | 0.86 | EPHX2 (0.88) | EPHX2SLC6A5KDM4ECNR1LPAR1 | |
| SCHEMBL10481762 | 0.86 | EPHX2 (0.88) | EPHX2SLC6A5KDM4ECNR1LPAR1 | |
| SCHEMBL3375110 | 0.86 | EPHX2 (0.88) | EPHX2SLC6A5KDM4ECNR1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083046-A2 | GALACTOSE CLUSTER-PHARMACOKINETIC MODULATOR TARGETING MOIETY FOR SIRNA | ARROWHEAD RESEARCH CORPORATION (US) | 2012-06-21 | — | — | WO | disclosed |