Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 14/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.65 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.64 |
| ▸ | VDR | P11473 | 1/20 | 0.64 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.61 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22738617 | 0.90 | GPBAR1 (0.81) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL19858469 | 0.90 | GPBAR1 (0.80) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL19858468 | 0.90 | GPBAR1 (0.80) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL10084602 | 0.89 | GPBAR1 (0.81) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL6364729 | 0.84 | EPHA2 (0.84) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL4326984 | 0.84 | EPHA2 (0.84) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL4326989 | 0.84 | EPHA2 (0.84) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL21444661 | 0.81 | NR1H4 (0.69) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL31603996 | 0.81 | GPBAR1 (0.61) | GPBAR1NR1H4ENPP2ABCB11EPHA2 | |
| SCHEMBL25706030 | 0.81 | GPBAR1 (0.72) | GPBAR1NR1H4ENPP2ABCB11EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010516-A1 | GROWTH HORMONE CONJUGATES | NOVO NORDISK HEALTH CARE AG (CH) | 2012-01-26 | — | — | WO | disclosed |