SCHEMBL10085757

SCHEMBL10085757

CC(C)(C)c1ccc2c(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)c3ccccc3c(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.41
CYP2D6 P10635 2/20 0.39
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ACHE P22303 3/20 0.36
GPR84 Q9NQS5 1/20 0.36
PGR P06401 1/20 0.35
RORA P35398 1/20 0.35
RORC P51449 1/20 0.35
RORB Q92753 1/20 0.35
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260717 1.00 KIF11 (0.41) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL10064003 0.98 KIF11 (0.40) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL10064012 0.98 KIF11 (0.40) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL10063874 0.97 KIF11 (0.39) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL10063876 0.97 KIF11 (0.39) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL9963823 0.91 TP53 (0.39) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL13615646 0.91 TP53 (0.37) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL12928329 0.91 TP53 (0.37) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL13615686 0.91 TP53 (0.37) KIF11CYP2D6TP53SMN1; SMN2ACHE
SCHEMBL10063930 0.91 TP53 (0.43) KIF11CYP2D6TP53SMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147989-B2 OLED device with stabilized green light-emitting layer GLOBAL OLED TECHNOLOGY LLC (US) 2012-04-03 US disclosed
US-8147989-B2 OLED device with stabilized green light-emitting layer GLOBAL OLED TECHNOLOGY LLC (US) 2012-04-03 US disclosed
WO-2010098879-A1 OLED DEVICE WITH STABILZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC. (US) 2010-09-02 WO disclosed
US-20100219748-A1 OLED DEVICE WITH STABILIZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC 2010-09-02 US disclosed
US-20100219748-A1 OLED DEVICE WITH STABILIZED GREEN LIGHT-EMITTING LAYER GLOBAL OLED TECHNOLOGY LLC 2010-09-02 US disclosed