Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GPR39 | O43194 | 12/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10086623 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EF2 | |
| SCHEMBL10086635 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10086733 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EGPR39MEN1 | |
| SCHEMBL10086735 | 0.82 | KDM4E (0.54) | ALDH1A1HPGDKDM4EKCNH3 | |
| SCHEMBL10086710 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10086638 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10086666 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL12140755 | 0.81 | JAK2 (0.53) | GPR39MEN1KMT2A | |
| SCHEMBL16503794 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10086674 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020786-A1 | PHARMACEUTICAL COMPOSITION | 日本新薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020787-A1 | MALIGNANT LYMPHOMA THERAPEUTIC AGENT | 日本新薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012005299-A1 | ROS TYROSINE KINASE INHIBITOR | 日本新薬株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |
| WO-2010090290-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | 日本新薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |