SCHEMBL10087154

SCHEMBL10087154

CC(C)(C)c1ccc2c(c1)c1cc(N(c3ccc4c(c3)c3cc(N(c5ccc6c(c5)c5cc(C(C)(C)C)ccc5n6-c5ccccc5)c5cccc6ccccc56)ccc3n4-c3ccccc3)c3cccc4ccccc34)ccc1n2-c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ PPARG P37231 3/20 0.35
▸ PGR P06401 1/20 0.34
▸ RORA P35398 1/20 0.34
▸ RORC P51449 1/20 0.34
▸ RORB Q92753 1/20 0.34
▸ SIGMAR1 Q99720 3/20 0.33
▸ KIF11 P52732 2/20 0.33
▸ PPARA Q07869 1/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ ADRA2A P08913 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ HTR2A P28223 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10087146 1.00 KDM4E (0.36) KDM4EATML3MBTL1PPARGPGR
SCHEMBL4400184 0.98 KDM4E (0.35) KDM4EATML3MBTL1PPARGPGR
SCHEMBL4398136 0.98 KDM4E (0.35) KDM4EATML3MBTL1PPARGPGR
SCHEMBL13382691 0.98 KDM4E (0.41) KDM4EATML3MBTL1PPARGPGR
SCHEMBL12559413 0.97 PGR (0.34) KDM4EATML3MBTL1PPARGPGR
SCHEMBL12559410 0.97 PGR (0.34) KDM4EATML3MBTL1PPARGPGR
SCHEMBL4398106 0.94 PGR (0.33) KDM4EATML3MBTL1PPARGPGR
SCHEMBL4400919 0.92 PGR (0.36) PPARGPGRRORARORCRORB
SCHEMBL4401050 0.91 PPARG (0.34) PPARGPGRRORARORCRORB
SCHEMBL4401059 0.91 PPARG (0.34) PPARGPGRRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8405070-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-26 — — US disclosed
US-8405070-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-26 — — US disclosed
US-8362474-B2 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-29 — — US disclosed
US-8362474-B2 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-29 — — US disclosed
US-20120032160-A1 ORGANIC FIELD EFFECT TRANSISTOR AND SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 — — US disclosed
US-20120032160-A1 ORGANIC FIELD EFFECT TRANSISTOR AND SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-09 — — US disclosed
US-8049206-B2 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-01 — — US disclosed
US-8049206-B2 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-11-01 — — US disclosed
US-20100084645-A1 COMPOSITE MATERIAL, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE COMPOSITE MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-08 — — US disclosed
US-20100084645-A1 COMPOSITE MATERIAL, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE COMPOSITE MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-04-08 — — US disclosed
US-7649197-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-19 — — US disclosed
US-7649197-B2 Composite material, and light emitting element and light emitting device using the composite material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-19 — — US disclosed
US-20090309093-A1 COMPOSITE MATERIAL, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE COMPOSITE MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-12-17 — — US disclosed
US-20090309093-A1 COMPOSITE MATERIAL, AND LIGHT EMITTING ELEMENT AND LIGHT EMITTING DEVICE USING THE COMPOSITE MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-12-17 — — US disclosed
US-20080254318-A1 Carbazole Derivative, and Light-Emitting Element and Light-Emitting Device Using the Carbzole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-16 — — US disclosed
US-20080254318-A1 Carbazole Derivative, and Light-Emitting Element and Light-Emitting Device Using the Carbzole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-16 — — US disclosed
US-20080099757-A1 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-01 — — US disclosed
US-20080099757-A1 Organic field effect transistor and semiconductor device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-01 — — US disclosed
WO-2007086534-A1 ORGANIC FIELD EFFECT TRANSISTOR AND SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-08-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080254318-A1 Carbazole Derivative, and Light-Emitting Element and Light-Emitting Device Using the Carbzole Derivative CYP2C19, CYP3A5, CYP3A4 KDM4E 2337/4885ATM 4554/4885L3MBTL1 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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