PGR
Progesterone receptor · P06401 · PGR on Sugi Atlas →
494,014 patent compounds predicted against PGR, 329,760 high-confidence (nearest known ligand ≥ 0.5)
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours | |
|---|---|---|---|
| Onapristone (SCHEMBL8740) | 1.00 | 13/20 | |
| Clocortolone Pivalate (SCHEMBL5120) | 1.00 | 10/20 | |
| Mifepristone (SCHEMBL16087) | 1.00 | 10/20 | |
| SCHEMBL8133 | 0.55 | 10/20 | |
| Fluocortolone (SCHEMBL4644) | 0.70 | 9/20 | |
| Fluocortolone (SCHEMBL8134) | 0.65 | 9/20 | |
| Diflucortolone (SCHEMBL3794) | 1.00 | 8/20 | |
| Diflucortolone (SCHEMBL3795) | 1.00 | 8/20 | |
| Diflucortolone (SCHEMBL3796) | 1.00 | 8/20 | |
| Prednicarbate (SCHEMBL3941) | 1.00 | 8/20 | |
| Prednicarbate (SCHEMBL3942) | 1.00 | 8/20 | |
| Alclometasone Dipropionate (SCHEMBL6833) | 1.00 | 8/20 | |
| Paramethasone Acetate (SCHEMBL7126) | 0.79 | 8/20 | |
| Methylprednisolone Aceponate (SCHEMBL3466) | 0.74 | 8/20 | |
| Diflucortolone 21-Valerate (SCHEMBL3015) | 0.73 | 8/20 | |
| Diflucortolone 21-Valerate (SCHEMBL13157) | 0.73 | 8/20 | |
| Diflucortolone 21-Valerate (SCHEMBL13158) | 0.73 | 8/20 | |
| SCHEMBL20554 | 0.58 | 8/20 | |
| Ciclesonide (SCHEMBL3688) | 1.00 | 7/20 | |
| Deflazacort (SCHEMBL4018) | 1.00 | 7/20 |
Clinical trials — most relevant to PGR by text similarity (a relevance ranking, not an exhaustive list)
Related proteins — ESM-2 sequence neighbours (a PGR binder may also engage these)
| Protein | Name | Similarity | |
|---|---|---|---|
| A7X8B3 | — | 1.000 | A7X8B3 → |
| A7X8C9 | — | 1.000 | A7X8C9 → |
| A7X8B5 | — | 1.000 | A7X8B5 → |
| A7X8B7 | — | 1.000 | A7X8B7 → |
| A7X8C4 | — | 1.000 | A7X8C4 → |
| A7XW25 | — | 1.000 | A7XW25 → |
| P06186 | — | 1.000 | P06186 → |
| Q00175 | — | 1.000 | Q00175 → |
| A7XW20 | — | 1.000 | A7XW20 → |
| A7XW16 | — | 1.000 | A7XW16 → |
| A7X8C7 | — | 1.000 | A7X8C7 → |
| A7X8D4 | — | 1.000 | A7X8D4 → |
| Q63449 | — | 1.000 | Q63449 → |
| A7X8B9 | — | 1.000 | A7X8B9 → |
| A7X8C2 | — | 1.000 | A7X8C2 → |
| A7X8D2 | — | 0.999 | A7X8D2 → |
| O97952 | — | 0.999 | O97952 → |
| O97776 | — | 0.999 | O97776 → |
| P07812 | — | 0.999 | P07812 → |
| P19091 | — | 0.998 | P19091 → |
| O97960 | — | 0.997 | O97960 → |
| Q9GKL7 | — | 0.997 | Q9GKL7 → |
| O97775 | — | 0.997 | O97775 → |
| Q6QT55 | — | 0.997 | Q6QT55 → |
| Q9TT90 | — | 0.996 | Q9TT90 → |
| Q9GLW0 | — | 0.996 | Q9GLW0 → |
| Q2VWA4 | — | 0.995 | Q2VWA4 → |
| TET3 | Methylcytosine dioxygenase TET3 | 0.995 | landscape → |
| Q8MIK0 | — | 0.994 | Q8MIK0 → |
| O14512 | — | 0.994 | O14512 → |