Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14180926 | 0.88 | SLC7A5 (0.51) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14180928 | 0.88 | SLC7A5 (0.51) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10087250 | 0.85 | PDE2A (0.51) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10087189 | 0.81 | PDE2A (0.47) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL26870949 | 0.77 | SLC2A1 (0.50) | ALDH1A1 | |
| SCHEMBL5924733 | 0.77 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2056155 | 0.77 | PDE2A (0.58) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL84428 | 0.77 | ALDH1A1 (0.65) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23058487 | 0.76 | PDE2A (0.47) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6123520 | 0.76 | PDE2A (0.44) | PDE2AALDH1A1SLC6A4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | disclosed |
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | CNR1, CNR2, GPR6 | PDE2A 3469/4885ALDH1A1 3325/4885SLC6A4 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.