Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087777 | 1.00 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL10087778 | 1.00 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL10087779 | 1.00 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL10087780 | 1.00 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL10087774 | 1.00 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL6896326 | 0.98 | CYP4F2 (0.47) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL6895404 | 0.94 | CYP4F2 (0.45) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL6895578 | 0.88 | CYP4F2 (0.40) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL6898839 | 0.83 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL6893080 | 0.81 | MMP8 (0.37) | CYP4F2CYP4A11L3MBTL1ABCB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107911-B2 | Prodrugs of heteraromatic compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2015-08-18 | — | — | US | disclosed |
| US-20120015866-A1 | Prodrugs of Heteraromatic Compounds | ALKERMES, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015866-A1 | Prodrugs of Heteraromatic Compounds | CYP2D6, CYP2B6, CYP3A4 | CYP4F2 41/4885CYP4A11 40/4885MAPT 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.