Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632437 | 0.81 | PLCG1 (0.45) | PLCG1CYP11B1LMNASMN1; SMN2KDM4E | |
| SCHEMBL15176127 | 0.81 | PLCG1 (0.42) | PLCG1CYP11B1LMNASMN1; SMN2KDM4E | |
| SCHEMBL1663588 | 0.76 | KDM4E (0.57) | PLCG1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL9596105 | 0.74 | PARP1 (0.56) | PLCG1LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2961058 | 0.74 | PLCG1 (0.49) | PLCG1LMNASMN1; SMN2KDM4EELANE | |
| SCHEMBL2718276 | 0.74 | PARP1 (0.56) | PLCG1LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10402120 | 0.74 | KDM4E (0.55) | PLCG1LMNASMN1; SMN2KDM4EELANE | |
| Potassium Ion SCHEMBL10402119 | 0.73 | PLCG1 (0.44) | PLCG1CYP11B1LMNASMN1; SMN2KDM4E | |
| SCHEMBL16202157 | 0.72 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2ALDH1A1POLBL3MBTL1 | |
| SCHEMBL3465036 | 0.70 | PLCG1 (0.56) | PLCG1LMNAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009111337-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2009-09-11 | — | — | WO | disclosed |