Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | AGER | Q15109 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402120 | 0.98 | KDM4E (0.55) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL10567562 | 0.87 | KDM4E (0.47) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL10567569 | 0.87 | KDM4E (0.47) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL10632437 | 0.83 | PLCG1 (0.45) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL9596105 | 0.83 | PARP1 (0.56) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL2961058 | 0.83 | PLCG1 (0.49) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL2718276 | 0.83 | PARP1 (0.56) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL8833877 | 0.82 | KDM4E (0.59) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| Potassium Ion SCHEMBL10402119 | 0.81 | PLCG1 (0.44) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 | |
| Benzene SCHEMBL7527131 | 0.81 | KDM4E (0.57) | KDM4ETDP1ALDH1A1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103508945-A | Preparation method of 2-chloro-4-methyl nicotinonitrile | BIOTALK CO LTD | 2014-01-15 | — | — | CN | claimed |
| US-20250092040-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-11999730-B1 | AKT1 modulators | ALTEROME THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174667-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |
| US-20230192611-A1 | MODULATORS OF HEMOGLOBIN | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-108200760-A | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | 英安塔制药有限公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-102007125-B | fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-105017151-A | Carbostyril compound | OTSUKA PHARMA CO LTD | 2015-11-04 | — | — | CN | disclosed |
| US-7888513-B2 | Condensation reaction by metal catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-10-14 | — | — | US | disclosed |
| WO-2010038465-A1 | 8-SUBSTITUTED ISOQUINOLINE DERIVATIVE AND USE THEREOF | 旭化成ファーマ株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |
| US-20090198070-A1 | Condensation Reaction by Metal Catalyst | OSAKA UNIVERSITY (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-1958940-A1 | CONDENSATION REACTION BY METAL CATALYST | Takasago International Corporation (JP) | 2008-08-20 | — | — | EP | disclosed |
| CN-1913898-A | Substituted piperazines | CHEMOCENTRYX INC (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-0429372-A1 | 2-Azolyl nicotinate derivatives as herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-05-29 | — | — | EP | disclosed |
| US-4851396-A | Fungicidal compositions based on nicotinic acid derivatives, new nicotinic acid derivatives and preparation thereof | RHONE-POULENC AGROCHIMIE (FR) | 1989-07-25 | — | — | US | disclosed |
| US-4080336-A | Process for the production of 2-chloronicotinic acid amide | LONZA LTD. (CH) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | KDM4E 2376/4885TDP1 1721/4885ALDH1A1 4692/4885 |
| US-20100261701-A1 | 8-Substituted isoquinoline derivative and the use thereof | RELA, NFKBIA, NFKB2 | KDM4E 2465/4885TDP1 1331/4885ALDH1A1 1380/4885 |
| US-20230192611-A1 | MODULATORS OF HEMOGLOBIN | HBG1, HBG2, HBB | KDM4E 2311/4885TDP1 4074/4885ALDH1A1 1650/4885 |
| US-20090198070-A1 | Condensation Reaction by Metal Catalyst | C9, CBR3, C1R | KDM4E 1848/4885TDP1 4766/4885ALDH1A1 2265/4885 |
| US-20250092040-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | KDM4E 2376/4885TDP1 1721/4885ALDH1A1 4692/4885 |
| US-11999730-B1 | AKT1 modulators | AKT1S1, AKT1, AKT2 | KDM4E 2376/4885TDP1 1721/4885ALDH1A1 4692/4885 |
| US-20240174667-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | KDM4E 2376/4885TDP1 1721/4885ALDH1A1 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.