Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806962 | 0.98 | SLC6A2 (0.47) | GSTP1ESR1ESR2ALOX5SLC6A2 | |
| SCHEMBL5400224 | 0.95 | GSTP1 (0.48) | GSTP1ESR1ESR2ALOX5SLC6A2 | |
| SCHEMBL5405311 | 0.91 | GSTP1 (0.52) | GSTP1ESR1ESR2ALOX5HSD17B1 | |
| SCHEMBL6617332 | 0.79 | ALDH1A1 (0.50) | SLC6A2CYP1A2ALDH1A1HPGDCYP2C19 | |
| SCHEMBL11146097 | 0.78 | TDP1 (0.54) | GSTP1ESR1ESR2ALOX5SLC6A2 | |
| SCHEMBL22634176 | 0.77 | SLC6A2 (0.58) | GSTP1ESR1ESR2ALOX5SLC6A2 | |
| SCHEMBL30603836 | 0.77 | ESR1 (0.71) | GSTP1ESR1ESR2ALOX5HSD17B1 | |
| SCHEMBL15902840 | 0.77 | ESR1 (0.71) | GSTP1ESR1ESR2ALOX5HSD17B1 | |
| SCHEMBL30239993 | 0.77 | ESR1 (0.71) | GSTP1ESR1ESR2ALOX5HSD17B1 | |
| SCHEMBL30239998 | 0.77 | ESR1 (0.71) | GSTP1ESR1ESR2ALOX5HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227433-B2 | Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation | PROMERUS, LLC (US) | 2019-03-12 | — | — | US | disclosed |
| EP-2137193-B1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI SA (FR) | 2017-08-09 | — | — | EP | disclosed |
| US-20160369026-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | PROMERUS, LLC (US) | 2016-12-22 | — | — | US | disclosed |
| US-9468890-B2 | Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation | PROMERUS, LLC (US) | 2016-10-18 | — | — | US | disclosed |
| EP-2870129-B1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | SUMITOMO BAKELITE CO (JP) | 2016-04-06 | — | — | EP | disclosed |
| EP-2870129-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | Promerus, LLC (US) | 2015-05-13 | — | — | EP | disclosed |
| EP-2268645-B1 | SUBSTITUTED DIHYDRO, TRIHYDRO AND TETRAHYDRO CYCLOALKYLOXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF AS ALLOSTERIC MODULATORS OF MGLUR | SANOFI SA (FR) | 2014-11-12 | — | — | EP | disclosed |
| US-20140042090-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | PROMERUS, LLC (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2014025735-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | PROMERUS, LLC (US) | 2014-02-13 | — | — | WO | disclosed |
| US-8642603-B2 | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI (FR) | 2014-02-04 | — | — | US | disclosed |
| US-8207181-B2 | Substituted dihydro, trihydro and tetrahydro cycloalkyloxazolopyrimidinones, preparation and use thereof | SANOFI (FR) | 2012-06-26 | — | — | US | disclosed |
| US-20110077257-A1 | SUBSTITUTED DIHYDRO, TRIHYDRO AND TETRAHYDRO CYCLOALKYLOXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-31 | — | — | US | disclosed |
| EP-2268645-A1 | SUBSTITUTED DIHYDRO, TRIHYDRO AND TETRAHYDRO CYCLOALKYLOXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF AS ALLOSTERIC MODULATORS OF MGLUR | Sanofi-Aventis (FR) | 2011-01-05 | — | — | EP | disclosed |
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-25 | — | — | US | disclosed |
| WO-2009110901-A1 | SUBSTITUTED DIHYDRO, TRIHYDRO AND TETRAHYDRO CYCLOALKYLOXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF AS ALLOSTERIC MODULATORS OF MGLUR | SANOFI-AVENTIS (FR) | 2009-09-11 | — | — | WO | disclosed |
| US-7192684-B2 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20040067436-A1 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077257-A1 | SUBSTITUTED DIHYDRO, TRIHYDRO AND TETRAHYDRO CYCLOALKYLOXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | CNR2, CNR1, GRIN2B | GSTP1 4056/4885ESR1 1095/4885ESR2 648/4885 |
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | GRM2, GRM1, GRIN2C | GSTP1 4277/4885ESR1 699/4885ESR2 491/4885 |
| US-20160369026-A1 | CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION | NOTUM, AGPS, WEE1 | GSTP1 1663/4885ESR1 4825/4885ESR2 4177/4885 |
| US-10227433-B2 | Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation | NOTUM, AGPS, WEE1 | GSTP1 1663/4885ESR1 4825/4885ESR2 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.