Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.83 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089373 | 0.92 | CYP1A2 (0.77) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL14471349 | 0.86 | CYP1A2 (0.69) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL14648333 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL22795105 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL11505512 | 0.76 | HSD17B10 (0.62) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL67608 | 0.76 | HSP90AA1 (0.74) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL10089372 | 0.74 | HSP90AA1 (0.56) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL1907836 | 0.74 | HSD17B10 (0.59) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL28903722 | 0.74 | HSD17B10 (0.59) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 | |
| SCHEMBL29577605 | 0.74 | HSD17B10 (0.59) | CYP1A2CYP2C9PRMT1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | PICALM, PARG, POLM | CYP1A2 4502/4885CYP2C9 3550/4885PRMT1 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.