Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 6/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089986 | 0.93 | MAPK8 (0.39) | MAPK8 | |
| SCHEMBL10089921 | 0.93 | HSD17B13 (0.40) | HSD17B13MAPK8EPHX2RIPK1MAPK1 | |
| SCHEMBL10089937 | 0.92 | HSD17B13 (0.40) | HSD17B13MAPK8EPHX2RIPK1MAPK1 | |
| SCHEMBL10089938 | 0.90 | HSD17B13 (0.39) | HSD17B13MAPK8EPHX2RIPK1MAPK1 | |
| SCHEMBL10090033 | 0.90 | PDE2A (0.35) | RIPK1MAPK1 | |
| SCHEMBL17122515 | 0.89 | MAPK8 (0.37) | HSD17B13MAPK8EPHX2 | |
| SCHEMBL10089982 | 0.89 | PPARG (0.39) | RIPK1 | |
| SCHEMBL15905592 | 0.88 | DHODH (0.37) | — | |
| SCHEMBL10089899 | 0.88 | HSD17B13 (0.40) | HSD17B13MAPK8EPHX2RIPK1MAPK1 | |
| SCHEMBL15905605 | 0.88 | HSD17B13 (0.40) | HSD17B13EPHX2RIPK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582695-B1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES WITH CYCLICAL SIDE CHAINS | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | HSD17B13 4352/4885MAPK8 4028/4885EPHX2 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.