SCHEMBL10089933

SCHEMBL10089933

Cc1cc(C#N)cc(C(=O)NCc2ccccc2)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 10/20 0.37
SLC2A3 P11169 10/20 0.37
SLC2A4 P14672 10/20 0.37
SLC2A2 P11168 4/20 0.36
IDH1 O75874 1/20 0.35
ELANE P08246 3/20 0.35
CNR2 P34972 2/20 0.34
MMP13 P45452 1/20 0.33
DHODH Q02127 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10089842 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2IDH1
SCHEMBL10090035 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2IDH1
SCHEMBL10089931 0.93 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2IDH1
SCHEMBL13085009 0.92 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2ELANE
SCHEMBL10075525 0.92 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2ELANE
SCHEMBL10089967 0.92 DHODH (0.36) IDH1CNR2MMP13DHODH
SCHEMBL10089887 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2ELANE
SCHEMBL29454974 0.92 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL798149 0.92 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL29454976 0.92 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791143-B2 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains DDT, ADCY1, ANTXR2 SLC2A1 3782/4885SLC2A3 3762/4885SLC2A4 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.