SCHEMBL10089963

SCHEMBL10089963

Cc1cc(C#N)cc(C(=O)NC(C)c2ccccc2)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1ccccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.35
CNR2 P34972 2/20 0.35
PHGDH O43175 1/20 0.35
CARM1 Q86X55 2/20 0.33
SLC2A1 P11166 6/20 0.33
SLC2A3 P11169 6/20 0.33
SLC2A4 P14672 6/20 0.33
SLC2A2 P11168 1/20 0.33
MAPK14 Q16539 1/20 0.32
PPARG P37231 2/20 0.32
P2RY12 Q9H244 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10076313 0.94 SLC2A1 (0.34) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL11928445 0.92 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10083881 0.90 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085420 0.90 SLC2A1 (0.34) CNR1CNR2SLC2A1SLC2A3SLC2A4
SCHEMBL10076311 0.89 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085547 0.89 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085283 0.89 SLC2A1 (0.35) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13085372 0.89 SLC2A1 (0.39) SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10076309 0.88 SLC2A1 (0.32) CNR1SLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL10089878 0.88 IDH1 (0.39) CNR1CNR2SLC2A1SLC2A3SLC2A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791143-B2 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains DDT, ADCY1, ANTXR2 CNR1 984/4885CNR2 1011/4885PHGDH 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.