Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985315 | 1.00 | PTGES (0.44) | PTGES | |
| SCHEMBL11985314 | 0.95 | PTGES (0.44) | PTGES | |
| SCHEMBL11985280 | 0.93 | PTGES (0.43) | PTGES | |
| SCHEMBL10091521 | 0.92 | PTGES (0.45) | PTGES | |
| SCHEMBL11985142 | 0.92 | PTGES (0.45) | PTGES | |
| SCHEMBL11985102 | 0.92 | PTGES (0.49) | PTGES | |
| SCHEMBL10091460 | 0.91 | PTGES (0.43) | PTGES | |
| SCHEMBL11985169 | 0.91 | PTGES (0.43) | PTGES | |
| SCHEMBL10091650 | 0.91 | PTGES (0.43) | PTGES | |
| SCHEMBL11985319 | 0.91 | PTGES (0.43) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022792-A1 | 2-(ARYLAMINO)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBOXAMIDE DERIVATIVES AND THEIR USE AS MPGES-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |